2000MPH UFO Incident Sparks U.S. Navy UFO Investigation

Considering the U.S. Navy has never released any official documents pertaining to unidentified flying objects, there’s some interesting reading below about how an unexplained UFO incident over the Pacific Ocean sparked an official investigation by the Office of Naval Intelligence in 1952…the contents of which are still classified.

The incident occurred over the area of ocean between the islands of Guam and Hawaii and involved the aircrews of two separate Navy aircraft witnessing two ‘disc shaped’ objects which ‘circled’ their aircraft twice and departed to the East at an approximate speed of 1500 to 2000 mph – on board the aircraft was Admiral Arthur Radford and Naval Secretary Dan Kimball who later convened a conference with the Chief of the Naval Research Admiral Calvin Bolster about making a full investigation of all Navy and Marine UFO reports.

There’s more details and newspaper articles about the UFO incident and subsequent investigation below, Project 1947′s Jan Aldrich also raises some extremely important points about the complete lack of declassified US Naval UFO documents and undisclosed O.N.I. UFO investigations.

via 2000MPH UFO Incident Sparks U.S. Navy UFO Investigation., page 1.

Welcome to life

Created by Tom Scott, and inspired by Jim Munroe’s Everyone in Silico and Rudy Rucker’s Postsingular.

Dietary supplements increase cancer risk

Erika Matich – Beta-carotene, selenium and folic acid – taken up to three times their recommended daily allowance, these supplements are probably harmless. But taken at much higher levels as some supplement manufacturers suggest, these three supplements have now been proven to increase the risk of developing a host of cancers.

“It’s not that these nutrients are toxic – they’re essential and we need them, but we need them in a certain balance,” says Tim Byers, MD, MPH, professor of epidemiology at the Colorado School of Public Health and associate director for prevention and control at the University of Colorado Cancer Center.

Byers is senior author of a commentary recently published in the Journal of the National Cancer Institute that discusses the clinical and policy implications of the increased cancer risk from high dose dietary supplements.

“We have a window into less than half of the biology of what these nutrients are doing,” Byers says. “We say generalized things about them, calling them an antioxidant or an essential mineral, but true biology turns out to be more complex than that. The effects of these supplements are certainly not limited to the label we give them. And, as we’ve seen, sometimes the unintended effects include increased cancer risk.”

Currently the FDA regulates dietary supplements as food, but, as Byers and colleagues suggest, supplements, especially at high doses, are more accurately described as inhabiting a mid-ground between food and drugs. Like drugs, supplement ingredients are biologically active – sometimes for better and sometimes for worse.

“We need to do a better job as a society in ensuring that the messages people get about value versus risk is accurate for nutritional supplements,” Byers says. “My conclusion is that taking high doses of any particular nutrient is more likely to be a bad thing than a good thing.”

via Dietary supplements increase cancer risk.

We are operating in the dark.  What we need is an easy way to test and better guidelines on what optimal levels.

Beyond the High-Speed Hard Drive: Topological Insulators Open a Path to Room-Temperature Spintronics

Strange new materials experimentally identified just a few years ago are now driving research in condensed-matter physics around the world. First theorized and then discovered by researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory Berkeley Lab and their colleagues in other institutions, these “strong 3-D topological insulators” – TIs for short – are seemingly mundane semiconductors with startling properties. For starters, picture a good insulator on the inside that’s a good conductor on its surface – something like a copper-coated bowling ball. A topological insulator’s surface is not an ordinary metal, however. The direction and spin of the surface electrons are locked together and change in concert. And perhaps the most surprising prediction is that the surface electrons cannot be scattered by defects or other perturbations and thus meet little or no resistance as they travel. In the jargon, the surface states remain “topologically protected” – they can’t scatter without breaking the rules of quantum mechanics. “One way that electrons lose mobility is by scattering on phonons,” says Alexei Fedorov, staff scientist for beamline 12.0.1 of Berkeley Lab’s Advanced Light Source ALS . Phonons are the quantized vibrational energy of crystalline materials, treated mathematically as particles. “Our recent work on a particularly promising topological insulator shows that its surface electrons hardly couple with phonons at all. So there’s no impediment to developing this TI for spintronics and other applications.”The TI in question is bismuth selenide, Bi2Se3, on whose surface electrons can flow at room temperature, making it an attractive candidate for practical applications like spintronics devices, plus farther-out ones like quantum computers. Much of the research on electron-phonon coupling in Bi2Se3 was conducted at beamline 12.0.1 by a team including Fedorov, led by Tonica Valla of Brookhaven National Laboratory. Their results are reported in Physical Review Letters. …

via Beyond the High-Speed Hard Drive: Topological Insulators Open a Path to Room-Temperature Spintronics « Berkeley Lab News Center.

Sugar makes you stupid

Elaine Schmidt – Attention, college students cramming between midterms and finals: Binging on soda and sweets for as little as six weeks may make you stupid.

A new UCLA rat study is the first to show how a diet steadily high in fructose slows the brain, hampering memory and learning — and how omega-3 fatty acids can counteract the disruption. The peer-reviewed Journal of Physiology publishes the findings in its May 15 edition.

“Our findings illustrate that what you eat affects how you think,” said Fernando Gomez-Pinilla, a professor of neurosurgery at the David Geffen School of Medicine at UCLA and a professor of integrative biology and physiology in the UCLA College of Letters and Science. “Eating a high-fructose diet over the long term alters your brain’s ability to learn and remember information. But adding omega-3 fatty acids to your meals can help minimize the damage.”

While earlier research has revealed how fructose harms the body through its role in diabetes, obesity and fatty liver, this study is the first to uncover how the sweetener influences the brain.

The UCLA team zeroed in on high-fructose corn syrup, an inexpensive liquid six times sweeter than cane sugar, that is commonly added to processed foods, including soft drinks, condiments, applesauce and baby food. The average American consumes more than 40 pounds of high-fructose corn syrup per year, according to the U.S. Department of Agriculture.

“We’re not talking about naturally occurring fructose in fruits, which also contain important antioxidants,” explained Gomez-Pinilla, who is also a member of UCLA’s Brain Research Institute and Brain Injury Research Center. “We’re concerned about high-fructose corn syrup that is added to manufactured food products as a sweetener and preservative.”

Gomez-Pinilla and study co-author Rahul Agrawal, a UCLA visiting postdoctoral fellow from India, studied two groups of rats that each consumed a fructose solution as drinking water for six weeks. The second group also received omega-3 fatty acids in the form of flaxseed oil and docosahexaenoic acid (DHA), which protects against damage to the synapses — the chemical connections between brain cells that enable memory and learning.

“DHA is essential for synaptic function — brain cells’ ability to transmit signals to one another,” Gomez-Pinilla said. “This is the mechanism that makes learning and memory possible. Our bodies can’t produce enough DHA, so it must be supplemented through our diet.”

The animals were fed standard rat chow and trained on a maze twice daily for five days before starting the experimental diet. The UCLA team tested how well the rats were able to navigate the maze, which contained numerous holes but only one exit. The scientists placed visual landmarks in the maze to help the rats learn and remember the way.

Six weeks later, the researchers tested the rats’ ability to recall the route and escape the maze. What they saw surprised them.

“The second group of rats navigated the maze much faster than the rats that did not receive omega-3 fatty acids,” Gomez-Pinilla said. “The DHA-deprived animals were slower, and their brains showed a decline in synaptic activity. Their brain cells had trouble signaling each other, disrupting the rats’ ability to think clearly and recall the route they’d learned six weeks earlier.”

The DHA-deprived rats also developed signs of resistance to insulin, a hormone that controls blood sugar and regulates synaptic function in the brain. A closer look at the rats’ brain tissue suggested that insulin had lost much of its power to influence the brain cells.

“Because insulin can penetrate the blood–brain barrier, the hormone may signal neurons to trigger reactions that disrupt learning and cause memory loss,” Gomez-Pinilla said.

He suspects that fructose is the culprit behind the DHA-deficient rats’ brain dysfunction. Eating too much fructose could block insulin’s ability to regulate how cells use and store sugar for the energy required for processing thoughts and emotions.

“Insulin is important in the body for controlling blood sugar, but it may play a different role in the brain, where insulin appears to disturb memory and learning,” he said. “Our study shows that a high-fructose diet harms the brain as well as the body. This is something new.”

Gomez-Pinilla, a native of Chile and an exercise enthusiast who practices what he preaches, advises people to keep fructose intake to a minimum and swap sugary desserts for fresh berries and Greek yogurt, which he keeps within arm’s reach in a small refrigerator in his office. An occasional bar of dark chocolate that hasn’t been processed with a lot of extra sweetener is fine too, he said.

Still planning to throw caution to the wind and indulge in a hot-fudge sundae? Then also eat foods rich in omega-3 fatty acids, like salmon, walnuts and flaxseeds, or take a daily DHA capsule. Gomez-Pinilla recommends one gram of DHA per day.

“Our findings suggest that consuming DHA regularly protects the brain against fructose’s harmful effects,” said Gomez-Pinilla. “It’s like saving money in the bank. You want to build a reserve for your brain to tap when it requires extra fuel to fight off future diseases.”

via Sugar makes you stupid.

Looks matter more than reputation when it comes to trusting people with our money

Our decisions to trust people with our money are based more on how they look then how they behave, according to new research from the University of Warwick.

In a paper recently published in the PLoS One journal, researchers from Warwick Business School, the University College London and Dartmouth College, USA, carried out a series of experiments to see if people made decisions to trust others based on their faces.

They found people are more likely to invest money in someone whose face is generally perceived as trustworthy, even when they are given negative information about this person’s reputation.

The team used a computer algorithm to create a set of 20 pairs of faces at opposing ends of the trustworthiness scale. This computer software modifies the apparent trustworthiness of faces by altering their features. The researchers were able to experimentally manipulate the unfakeable features (those related to shape of the face) that make a face look trustworthy or untrustworthy. These 40 faces were then used in a series of trust games with human participants.

Each volunteer was given a sum of money and told they could invest any part of the amount in a trustee whose face appeared on the screen. Any amount they invested would be tripled and volunteers were told it was then up to the trustee to decide how much to send back to them. Thus participants had an incentive to invest only in trustees who could be expected to return more than the invested amount.

The researchers found that 13 out of 15 participants invested more, on average, in the trustworthy identities. In a second experiment, the researchers gave the volunteers information about whether the trustees had good or bad histories. Even with this inside information, the average amount invested in those who looked ‘trustworthy’ was 6% higher.

Dr Chris Olivola from the University of Warwick’s Warwick Business School said: “Trustees with good and bad histories benefitted equally from trustworthy-looking facial features. The temptation to judge strangers by their faces is hard to resist. Trustworthiness is one of the most important traits for social and economic interactions and our study examines whether people take potentially costly actions in line with their face-based trustworthiness judgments.

“It seems we are still willing to go with our own instincts about whether we think someone looks like we can trust them.”

via Looks matter more than reputation when it comes to trusting people with our money.

Drugs from lizard saliva reduces the cravings for food

In a study with rats published in the Journal of Neuroscience, Assistant Professor Karolina Skibicka and her colleagues show that exendin-4 effectively reduces the cravings for food.

Karolina Skibicka – A drug made from the saliva of the Gila monster lizard is effective in reducing the craving for food. Researchers at the Sahlgrenska Academy, University of Gothenburg, have tested the drug on rats, who after treatment ceased their cravings for both food and chocolate.

An increasing number of patients suffering from type 2 diabetes are offered a pharmaceutical preparation called Exenatide, which helps them to control their blood sugar. The drug is a synthetic version of a natural substance called exendin-4, which is obtained from a rather unusual source – the saliva of the Gila monster lizard (Heloderma suspectum), North America’s largest lizard.

Researchers at the Sahlgrenska Academy at the University of Gothenburg, have now found an entirely new and unexpected effect of the lizard substance. …

In a study with rats published in the Journal of Neuroscience, Assistant Professor Karolina Skibicka and her colleagues show that exendin-4 effectively reduces the cravings for food.

“This is both unknown and quite unexpected effect,” comments an enthusiastic Karolina Skibicka:

” Our decision to eat is linked to the same mechanisms in the brain which control addictive behaviours. We have shown that exendin-4 affects the reward and motivation regions of the brain” …

The implications of the findings are significant” states Suzanne Dickson, Professor of Physiology at the Sahlgrenska Academy: “Most dieting fails because we are obsessed with the desire to eat, especially tempting foods like sweets. As exendin-4 suppresses the cravings for food, it can help obese people to take control of their weight,” suggests Professor Dickson. …

Research on exendin-4 also gives hope for new ways to treat diseases related to eating disorders, for example, compulsive overeating.

Another hypothesis for the Gothenburg researchers’ continuing studies is that exendin-4 may be used to reduce the craving for alcohol.

“It is the same brain regions which are involved in food cravings and alcohol cravings, so it would be very interesting to test whether exendin-4 also reduces the cravings for alcohol,” suggests Assistant Professor Skibicka.

via Drugs from lizard saliva reduces the cravings for food.

 

Why omega-3 oils help at the cellular level

Scott LaFee – For the first time, researchers at the University of California, San Diego have peered inside a living mouse cell and mapped the processes that power the celebrated health benefits of omega-3 fatty acids. More profoundly, they say their findings suggest it may be possible to manipulate these processes to short-circuit inflammation before it begins, or at least help to resolve inflammation before it becomes detrimental.

The work is published in the May 14, 2012 online Early Edition of the Proceedings of the National Academy of Sciences.

The therapeutic benefits of omega-3 fatty acids, which are abundant in certain fish oils, have long been known, dating back to at least the 1950s, when cod liver oil was found to be effective in treating ailments like eczema and arthritis. In the 1980s, scientists reported that Eskimos eating a fish-rich diet enjoyed better coronary health than counterparts consuming mainland foods.

“There have been tons of epidemiological studies linking health benefits to omega-3 oils, but not a lot of deep science,” said Edward A. Dennis, PhD, distinguished professor of pharmacology, chemistry and biochemistry. “This is the first comprehensive study of what fish oils actually do inside a cell.”

The scientists fed mouse macrophages – a kind of white blood cell – three different kinds of fatty acid: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (AA). EPA and DHA are major polyunsaturated omega-3 fatty acids, essential to a broad range of cellular and bodily functions, and the primary ingredient in commercial fish oil dietary supplements. AA is a polyunsaturated omega-6 fatty acid prevalent in the human diet.

In high levels, fatty acids are toxic, so cells typically sequester them as phospholipids in their membranes. When stimulated, however, the fatty acids may be released, provoking a cascading inflammatory response. Acute or limited inflammation is, of course, a vital immunological response to physical damage or invasive pathogens. But chronic inflammation is harmful and a common element of almost every disease, from diabetes to cancer.

After supplementing the mouse macrophages with fatty acids, the scientists stimulated them to produce an inflammatory response. They discovered that omega-3 fatty acids inhibit an enzyme called cyclooxygenase (COX), which produces the prostaglandin hormones that spark inflammation. The action is similar to what happens when one takes an aspirin, which disrupts the COX-2 signaling pathway, thus reducing inflammation and pain.

On the other hand, Dennis and co-author Paul C. Norris, a graduate student in the chemistry and biochemistry department and the molecular pharmacology training program, discovered that omega-3 oils do not inhibit another group of enzymes called lipoxygenases (LOX), which are also produced by stimulated macrophages. One type of generated LOX enzyme in turn produces fat-signaling molecules called leukotrienes, which are pro-inflammatory. But Norris noted that LOX enzymes may also generate anti-inflammatory compounds called resolvins from EPA and DHA.

These observations, he said, are also helpful in identifying potential adverse effects from taking fish oil. Since omega-3 fatty acids possess overlapping functions with COX inhibitor drugs, with well-known side effects, using both in combination can produce unexpected consequences.

It is this parsing of what’s happening inside cells that Dennis called “ground-breaking.”

“We’ve been able to look inside a cell, see what fish oils do and determine that the process of inflammation at this level may be manipulatable,” he said. “Now, we need to learn if we can fine-tune that process so we can use omega-3 oils to reduce the production of pro-inflammatory prostaglandins and boost the production of anti-inflammatory resolvins.”

via Why omega-3 oils help at the cellular level.

My nutritionist really wants me to start taking cod liver oil. I already take flax oil every morning. Here is an interesting summary of the benefits and risks of the two: Cod liver oil contains two omega-3 fats called docosahexaenoic acid, or DHA, and eicosapentaenoic acid, or EPA, while flaxseed oil contains a different omega-3 fat called alpha-linolenic acid, or ALA. The body needs all three of these fatty acids for different purposes. The body can convert the ALA in flaxseed oil into EPA and DHA, though in much smaller quantities than the same amount cod liver oil naturally contains. Cod liver oil, however, does not contain ALA nor the resources for the body to produce it. …

Large doses of flaxseed oil have been associated with diarrhea and loose stools. Allergic reactions and cases of anaphylaxis have also occurred from flaxseed oil consumption. Cod liver oil poses certain health risks that other forms of fish oil do not. Coming from the fish’s liver as opposed to the body, as in other fish oils, cod liver oil contains potentially excessive amounts of vitamin A in the form of retinol, which can be toxic in high enough doses and has been associated with a variety of health risks, including liver problems, lowered bone density and birth defects.

via Liverstrong.com